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CAS Number:
2172651-73-7
Purity:
≥98%
Molecular Weight:
437
Alternative Names:
RMC4550,(3-((3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl)-6-(2,3-dichlorophenyl)-5-methylpyrazin-2-yl)methanol
- Data sheet: View or download
- MSDS: View or download
Product Description:
RMC-4550 is a potent, selective and allosteric inhibitor of SHP2 (IC50 = 0.583 nM). RMC-4550 inhibits the activity of full-length wild-type SHP2 enzyme activated by a di-phosphotyrosine peptide, but lacks activity against the free catalytic domain of SHP2.
Storage Temperature:
-20°C