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ACE-2 Substrate, Fluorogenic

Catalogue number:
Supplier:
BioVision
Size:
5 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
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Purity:

≥95% by HPLC

Molecular Weight:

697

Alternative Names:

Mca-Ala-Pro-Lys(Dnp)-OH [Mca=(7-methoxycoumarin-4-yl)acetyl;Dnp=2,4-dinitrophenyl],Mca-APK(Dnp),ACE2 Substrate

Product Description:

ACE-2 substrate, Fluorogenic is a useful fluorogenic substrate for angiotensin converting enzyme-2 (ACE-2), a zinc-dependent carboxypeptidase with 42% amino acid sequence identity to ACE1. Unlike Mca-YVADAPK(Dnp)-OH (Cat. No. B2717), this substrate is not cleaved by caspases. This peptide substrate contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group. This substrate is useful for inhibitor screening and kinetic analysis. Ex: 328 nm, Em: 393 nm.

Storage Temperature:

-20°C