Anti-Caspase-3 (Active) Biotinylated Antibody
Catalogue number:
A2116-30T
Supplier:
BioVision
Size:
100 µl _$$_
Product is available in:
N/A
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This product is no longer available to order.
Applications:
ELISA
Antibody Host:
Rabbit
Species Reactivity:
Human
Antibody Isotype:
IgG
Antibody Type:
Polyclonal
Immunogen:
Synthetic peptide mapping to the N-terminus adjacent to the cleavage site of human caspase-3
- Data sheet: View or download
Product Description:
The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
Storage Temperature:
-20°C
