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480-39-7
≥95%
A solid
256.3
(2s)-2,3-dihydro-5,7-dihydroxy-2-phenyl-4h-1-benzopyran-4-one, (+)-pinocembrin, dihydrochrysin, nsc 279005
- Data sheet: View or download
- MSDS: View or download
A flavonoid with diverse biological activities; induces apoptosis in, and inhibits the migration of, SKOV3 ovarian cancer cells at 200 µM; reduces lesion volume, as well as brain microglial activation and production of IL-1β, IL-6, and TNF-α in a mouse model of collagenase-induced ICH at 5 mg/kg; prevents increases in plasma and kidney MDA levels, glomeruli lobulation, mesangial expansion, and tubule vacuolization and occlusion, and it decreases hepatic cholesterol, triglyceride, and LDL levels in a rat model of diabetic nephropathy; reduces pulmonary edema, as well as neutrophil, lymphocyte, and macrophage infiltration in a mouse model of LPS-induced lung injury at 20 and 50 mg/kg
-20°C