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Custom plasmid construction: Syn2Clone

System Biosciences (SBI) provide a convenient custom gene or sequence synthesis service. Cloned into any of SBI's well-validated viral or non-viral vectors, the Syn2Clone™ custom plasmid construction service enables affordable, easy synthesis and cloning in as little as two weeks.

Benefits of using the Syn2Clone service
• Custom gene synthesis and subcloning in as little as two weeks
• Custom constructs using any of SBI’s well-validated vectors, such as pCDH lentivectors, AAV, piggyBac, Minicircle, PhiC31 integrase vectors and more
• Easy - just send your sequence

  Features Viral systems Non-viral systems

Integrating vectors

Great for general gene or noncoding RNA functional studies and applications where heritable expression is desired Lentivectors
  • High-titre and reliable
  • Random integration
  • Limited insert size
  • High copy number
PiggyBac Transposon
  • Easy, consistent transgenesis
  • Random integration
  • Unlimited insert size
  • High copy number
PhiC31 integrase system
  • One-step single-copy integration
  • Site-specific integration
  • Unlimited insert size
  • Single copy number

Non-integrating vectors

Great for sensitive applications, such as gene therapy, that need to avoid potential host gene disruptions due to vector integration AAV vectors
  • Effective gene delivery without viral integration
  • Limited insert size
  • High copy number
Enhanced episomal vectors
  • Easy episomal expression
  • Unlimited insert size
  • High copy number
Minicircle technology
  • Episomal expression free from foreign DNA
  • Unlimited insert size
  • High copy number


Contact our specialists
To discuss a custom synthesis project, please contact our custom service team.

Material available for download
System Biosciences gene delivery and expression brochure