Custom plasmid construction - Syn2Clone™

Cambridge Bioscience offers access to a convenient custom gene or sequence synthesis service from System Biosciences. Cloned into any of System Biosciences' well-validated viral or nonviral vectors, the Syn2Clone™ custom plasmid construction service enables affordable, easy synthesis and cloning in as little as two weeks.

Benefits of using this Syn2Clone™ service
• Custom gene synthesis and subcloning in as little as two weeks
• Affordable
• Uses any of SBI’s well-validated vectors
• Easy

	Viral systems	Non-viral systems
Integrating vectors Great for general gene or noncoding RNA functional studies and applications where heritable expression is desired	Lentivectors high-titre and reliable • Random integration • Limited insert size • High copy number	PiggyBac™Transposon Easy, consistent transgenesis • Random integration • Unlimited insert size • High copy number
		PhiC31 integrase system One-step single-copy integration • Site-specific integration • Unlimited insert size • Single copy number
Nonintegrating Vectors Great for sensitive applications, such as gene therapy, that need to avoid potential host gene disruptions due to vector integration	AAV vectors Effective gene delivery without viral integration • Limited insert size • High copy number	Enhanced episomal vectors Easy episomal expression • Unlimited insert size • High copy number
		Minicircle technology Episomal expression free from foreign DNA • Unlimited insert size • High copy number

Contact our specialists
To discuss a custom synthesis project, please contact our System Bioscience specialist.