Custom plasmid construction: Syn2Clone

System Biosciences (SBI) provide a convenient custom gene or sequence synthesis service. Cloned into any of SBI's well-validated viral or non-viral vectors, the Syn2Clone™ custom plasmid construction service enables affordable, easy synthesis and cloning in as little as two weeks.

Benefits of using the Syn2Clone service
• Custom gene synthesis and subcloning in as little as two weeks
• Custom constructs using any of SBI’s well-validated vectors, such as pCDH lentivectors, AAV, piggyBac, Minicircle, PhiC31 integrase vectors and more
• Easy - just send your sequence

	Features	Viral systems	Non-viral systems
Integrating vectors	Great for general gene or noncoding RNA functional studies and applications where heritable expression is desired	Lentivectors High-titre and reliable Random integration Limited insert size High copy number	PiggyBac Transposon Easy, consistent transgenesis Random integration Unlimited insert size High copy number
Integrating vectors			PhiC31 integrase system One-step single-copy integration Site-specific integration Unlimited insert size Single copy number
Non-integrating vectors	Great for sensitive applications, such as gene therapy, that need to avoid potential host gene disruptions due to vector integration	AAV vectors Effective gene delivery without viral integration Limited insert size High copy number	Enhanced episomal vectors Easy episomal expression Unlimited insert size High copy number
Non-integrating vectors			Minicircle technology Episomal expression free from foreign DNA Unlimited insert size High copy number

Contact our specialists
To discuss a custom synthesis project, please contact our custom service team.

Material available for download
System Biosciences gene delivery and expression brochure

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