Through our partner AnaBios, we provide guaranteed high-quality human lung tissues, to help generate highly valuable data and early human insights into a drug’s efficacy and safety in respiratory conditions before clinical trials.
Working with accredited transplant centres, AnaBios offers cryopreserved, precision-cut lung slices processed using a vibratome and slices generated are stored at -196°C with a RIN (RNA Integrity Numbers) score greater than 7.
AnaBios obtains all biospecimens from fully consented donors, directly from the original source with a traceable and transparent tissue origin. All transplant centres are accredited and fully compliant with local laws for human biospecimen collection. Samples are available in frozen formalin-fixed and RNAlater®️ formats.
Benefits of using these respiratory biospecimens
• Guaranteed high-quality
• Fully traceable and transparent tissue origin
• All biospecimens obtained directly from original source
• From accredited transplant centres in USA
• Guaranteed compliance with local laws for human biospecimen collection
• Customised approach to adapt projects to exact customer requirements
• Avoids challenges of data interpretation encountered with animal models
Preparation and storage of PLCS
• Asthma, Chronic Obstructive Pulmonary Disease (COPD), fibrotic lung diseases (Idiopathic Pulmonary Fibrosis (IPF)), Lymphangioleiomyomatosis (LAM) and infective lung diseases (cystic fibrosis, pneumonia)
• Assess efficacy/safety on genuine human targets
• Generate reliable quantitative human data on potency and selectivity of potential drugs
Left: Viability staining of freshly sliced PCLS. Right: cryopreserved PCLS after thawing from the same donor.
Material available for download
Human precision-cut lung tissue slices brochure
Discuss a custom project
To discuss a custom project further, please contact our biospecimen specialists.
Note: product availability depends on country - see product detail page.
|Details||Cat number & supplier||Size||Price|
|Human Lung Healthy Tissue LUN-501LN · AnaBios Corporation||
|Human Lung Diseased Tissue LUN-502LD · AnaBios Corporation||
|Human Precision Cut Lung Slices - Healthy Tissue LUN-503LNpcls · AnaBios Corporation||
|Human Precision Cut Lung Slices - Healthy Tissue LUN-504LDpcls · AnaBios Corporation||