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ROCK Activity Assay Kit Citations

Yang, C. et al. (2016). Adropin reduces paracellular permeability of rat brain endothelial cells exposed to ischemia-like conditions. Peptides. doi:10.1016/j.peptides.2016.03.009.

Özdemir, A. et al. (2016). Cardiac glycoside-induced cell death and Rho/Rho kinase pathway: Implication of different regulation in cancer cell lines. Steroids. doi:10.1016/j.steroids.2016.03.015.

Weng, C. H. et al. (2016). Cigarette smoke inhibits ROCK2 activation in T cells and modulates IL-22 production.Mol Immunol. 71:115-122.

Liu, Y. et al. (2015). ROCK inhibition impedes macrophage polarity and functions. Cell Immunol.doi:10.1016/j.cellimm.2015.12.005.

Muñoz, A. et al. (2015). Aging-related increase in Rho kinase activity in the nigral region is counteracted by physical exercise.J Gerontol A Biol Sci Med Sci. doi:10.1093/gerona/glv179.

Johnson, K. M. & Crocker, S. J. (2015). TIMP-1 couples RhoK activation to IL-1β-induced astrocyte responses.Neurosci Lett.  609:165-170.

Al-Shboul, O. (2015). The role of the RhoA/ROCK pathway in gender-dependent differences in gastric smooth muscle contraction. J Physiol Sci. doi:10.1007/s12576-015-0400-9.

Stamatovic, S. M. et al. (2015). PDCD10 (CCM3) regulates brain endothelial barrier integrity in cerebral cavernous malformation type 3: role of CCM3-ERK1/2-cortactin cross-talk. Acta Neuropathol.doi:10.1007/s00401-015-1479-z.

Li, H. et al. (2015). KAP regulates ROCK2 and Cdk2 in an RNA-activated glioblastoma invasion pathway. Oncogene. 34:1432-1441.

Singh, J. et al. (2015). Bimodal effect of oxidative stress in internal anal sphincter (IAS) smooth muscle. Am JPhysiol Gastrointest Liver Physiol. doi: 10.1152/ajpgi.00125.2015.

Jasińska-Stroschein, M. et al. (2015). Rosuvastatin intensifies the beneficial effects of Rho-kinase inhibitor in reversal of monocrotaline-induced pulmonary hypertension. Arch Med Sci.   doi:10.5114/aoms.2015.49740.

Sasahara, T. et al. (2015). Epidermal growth factor induces Ca2+ sensitization through Rho-kinase-dependentphosphorylation of myosin phosphatase target subunit 1 in vascular smooth muscle. Eur J Pharmacol. doi:10.1016/j.ejphar.2015.05.042.

Wang, Z. C. et al. (2015). 28-Day hindlimb unweighting reduces expression of Rho kinase and inhibits its effects in femoral artery of rat.  J Physiol Biochem. doi:10.1007/s13105-015-0398-8.

Aoqui, C. et al. (2014). Microvascular dysfunction in the course of metabolic syndrome induced by high-fat diet. Cardiovasc Diabetol. 13:1-11.

Sai, X. et al. (2014).  Junctionally restricted RhoA activity is necessary for apical constriction during phase 2 inner ear placode invagination. Dev Biol. 394:206-216.

Moreau, S. et al. (2014). N-[11 C]-methyl-hydroxyfasudil is a potential biomarker of cardiac hypertrophy.  NuclMed Biol. 42:192-197.

Jasińska-Stroschein, M. et al. (2014). Concurrent Rho-kinase and tyrosine kinase platelet-derived growth factor inhibition in experimental pulmonary hypertension. Pharmacology. 93:145-150.

Seo, J. H. et al. (2014). Directing stem cell differentiation by changing the molecular mobility of supramolecularsurfaces. Adv Healthc Mater. doi: 10.1002/adhm.201400173.

Bouchareb, R. et al. (2014). Mechanical strain induces the production of spheroid mineralized microparticles in the aortic valve through a RhoA/ROCK-dependent mechanism.  J Mol Cell Cardiol. 67:49-59.

Weber, M et al. (2014). MiRNA-155 targets myosin light chain kinase and modulates actin cytoskeleton organization in endothelial cells. Am. J. Physiol. Heart Circ. Physiol. 306:H1192-H1203 (#STA-416).

Narimatsu, T. et al. (2013). Disruption of Cell-Cell Junctions and Induction of Pathological Cytokines in the Retinal Pigment Epithelium of Light-Exposed Mice. Invest. Opthalmol. Vis. Sci. 54:4555-4562 (#STA-416).

Singh, J. et al. (2013). Role of PKC and RhoA/ROCK Pathways in the Spontaneous Phasic Activity in the Rectal Smooth Muscle. Am J Physiol Gastrointest Liver Physiol. 304:G723-G731 (#STA-416).

Barcia, C. et al. (2012). ROCK/Cdc42-Mediated Microglial Motility and Gliapse Formation Lead to Phagocytosis of Degenerating Dopaminergic Neurons in vivo. Sci Rep. 2:809.

Zhang, W. et al. (2012). The Small GTPase RhoA Regulates the Contraction of Smooth Muscle Tissues by Catalyzing the Assembly of Cytoskeletal Signaling Complexes at Membrane Adhesion Sites. J. Biol. Chem. 287: 33966-34008 (#STA-416).

Burger, D. et al. (2012). Microparticles Induce Cell Cycle Arrest Through Redox-Sensitive Processes in Endothelial Cells: Implications in Vascular Senescence. JAHA. 1: e001842 (#STA-416).

DiPaolo, B.C. et al. (2012). Rho Kinase Signaling Pathways During Stretch in Primary Alveolar Epithelia. Am J Lung Cell Mol Physiol. 302: L992-L1002 (#STA-416).

Burger, D. et al. (2011). Endothelial Microparticle Formation by Angiotensin II is Mediated via Ang II Receptor Type I/NADPH Oxidase/Rho Kinase Pathways Targeted to Lipid Rafts. Arterioscler Thromb Vasc Biol. 31:1898-1907 (#STA-416).

Yotova, I.Y. et al. (2011). Abnormal Activation of Ras/Raf/MAPK and RhoA/ROCKII Signaling Pathways in EutopicEndometrial Stromal cells of Patients with Endometriosis. Hum. Reprod. 10.1093/humrep/der010 (#STA-416)

Haas, B. et al. (2009). Protein Kinase G Controls Brown Fat Cell Differentiation and Mitochondrial Biogenesis. Sci. Signal. 2:ra78 (#STA-416)