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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1191237-69-0
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
291.3
Alternative Names:
2-c-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-d-altrononitrile
Product Description:
An antiviral nucleoside analog; metabolized to an active triphosphate form that induces RNA chain termination and inhibits viral polymerases; active against MERS-CoV and SARS-CoV in infected primary HAE cells (EC50s = 0.86 and 0.18 µM, respectively); reduces viral plaque formation in SARS-CoV-2-infected Vero E6 and Calu-3 2B4 cells (EC50s = 0.42 and 0.62 mM, respectively); cytoprotective against HCV, YFV, DENV-2, influenza A, and parainfluenza 3 in cell-based assays (EC50s = 4.1, 11, 9.46, 27.9, and 1.71 µM, respectively)
Storage Temperature:
-20°C