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CMPD-1

Catalogue number:
Supplier:
BioVision
Size:
5 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
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CAS Number:

41179-33-3

Purity:

≥99%

Molecular Weight:

349

Alternative Names:

4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide; 2'-fluoro-N-(4-hydroxyphenyl)-[1,1'-biphenyl]-4-butanamide; Mitogen-activated protein kinase-activated protein kinase 2a Inhibitor; MK2a Inhibitor

Product Description:

MK2a inhibitor is a substrate-selective inhibitor of p38α MAPK that selectively inhibits p38α-dependent phosphorylation of mitogen-activated protein kinase-activated protein kinase 2 (MK2a) with a K(i)(app) of 330 nM. It does not inhibit the phosphorylation of ATF-2 and MBP. It inhibits proliferation of U87, A172, and U251 glioblastoma cells with EC₅₀ values of 0.6-1 µM by inhibition of tubulin polymerization and induction of apoptosis.

Storage Temperature:

-20°C

CMPD-1
CMPD-1