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CAS Number:
185351-19-3
Purity:
98%
Molecular Weight:
360
Alternative Names:
N-(1,4-Dihydro-1,4-dioxo-2-naphthalenyl)-L-tryptophan; (2S)-2-[(1,4-dioxonaphthalen-2-yl)amino]-3-(1H-indol-3-yl)propanoic acid; 1,4-naphthoquinon-2-yl-l-tryptophan
- Data sheet: View or download
- MSDS: View or download
Product Description:
NQTrp is an inhibitor of amyloid β (Aβ) oligomerization and fibrillization, with an IC₅₀ of 50 nM for formation of fibrils from Aβ1-42. It reduces the cytotoxic effect of Aβ oligomers in rat PC12 neuronal cell line. It also increases the life span and completely abolishes defective locomotion in a transgenic Alzheimer's disease Drosophila model.
Storage Temperature:
-20°C
