Anti-Smad4 Rabbit Monoclonal Antibody
Catalogue number:
A1605-50
Supplier:
BioVision
Size:
50 µl _$$_
Product is available in:
N/A
Shipping is calculated in checkout
This product is no longer available to order.
Applications:
WB, IHC
Antibody Host:
Rabbit
Species Reactivity:
Human
Antibody Isotype:
Rabbit IgG
Antibody Type:
Monoclonal
Immunogen:
A peptide corresponding to the C-terminus of human Smad4
- Data sheet: View or download
Product Description:
Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF-β and activin-mediated growth modulation. Smad4 has been shown to mediate all of the above activities throµgh interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members.
Storage Temperature:
-20°C
