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Anti-Integrin beta-1 Rabbit Monoclonal Antibody

Supplier:
Catalogue number:
A1598-50
Size:
50 µl
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£364.00 Estimated delivery Wed 28 Apr
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Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognise the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro). When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process and the formation of mineralised bone nodules. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1.

Product Type:

Antibodies

Species Reactivity:

Human

Storage Temp:

-20°C

Antibody Host:

Rabbit

Antibody Isotype:

Rabbit IgG

Formulation:

In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Antibody Type:

Monoclonal

Clone Number:

RM285

UNSPSC Code:

12352203

A1598-50

A1598-50