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Anti-CD20 Rabbit Monoclonal Antibody

Supplier:
Catalogue number:
A1594-50
Size:
50 µl
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£364.00 Estimated delivery Wed 28 Apr
Shipping is calculated in checkout

It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This mAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localisation in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin s disease, particularly of lymphocyte predominant type.

Product Type:

Antibodies

Species Reactivity:

Human

Storage Temp:

-20°C

Antibody Host:

Rabbit

Antibody Isotype:

Rabbit IgG

Formulation:

In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Antibody Type:

Monoclonal

Clone Number:

RM272

UNSPSC Code:

12352203

BioVision A1594-50

BioVision A1594-50