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Human CellExp™ CD19, Fc Tag, Rhesus macaque recombinant

Supplier:
Catalogue number:
P1329-50
Size:
50 µg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£569.00 Estimated delivery Wed 28 Apr
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B-lymphocyte antigen CD19 (CD19) is also known as B-lymphocyte surface antigen B4, Differentiation antigen CD19 and T-cell surface antigen Leu-12, which is a single-pass type I membrane protein and contains two Ig-like C2-type (immunoglobulin-like) domains. CD19 forms a complex with CD21, CD81 and CD225 in the membrane of mature B cells. CD19 interacts with GRB2 and SOS when phosphorylated on Tyr-348 and/or Tyr-378. CD19 also interacts with PLCG2 when phosphorylated on Tyr-409. CD19 is an important pan B cell marker and co-stimulatory protein in humans and mice. CD19 is a hallmark differentiation antigen of the B cell lineage and positively regulates antigen receptor signal transduction in mature B cells. CD19 defines signaling thresholds for the Ag receptor as well as other cell surface receptors that regulate B lymphocyte selection, activation, and differentiation. Defects in CD19 are a cause of hypogammaglobulinemia.

Product Type:

Proteins and peptides

Alternative Names:

CD19, B4, CVID3, MGC12804

Storage Temp:

-20°C

Molecular Weight:

56.7

UNSPSC Code:

12352202

BioVision P1329-50

BioVision P1329-50