ODC is pyridoxal phosphate dependent amino acid deacarboxylase, which catalyses the conversion of ornithine to putrescine. It is the first and rate-limiting step in the polyamine biosynthetic pathway. Polyamines are involved in processes such as cell growth, differentiation and synthesis of macromolecules. Overexpression of ODC is known to play role in cancers and inflammation.
Proteins and peptides