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Human CellExp™ Lipoprotein Lipase, Human Recombinant

Supplier:
Catalogue number:
P1309-10
Size:
10 µg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£441.00 Estimated delivery Wed 21 Apr
Shipping is calculated in checkout

LPL is a lipoprotein lipase, which is expressed in the heart, muscle, and adipose tissue. LPL acts as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Type I hyperlipoproteinemia is a result of severe mutations which cause LPL deficiency, whereas less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. Lipoprotein lipase (LPL) is a fundamental enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. LPL also promotes the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF) secretion and induction of vascular smooth muscle cell proliferation.

Product Type:

Proteins and peptides

Alternative Names:

Lipoprotein lipase, LPL, LIPD, HDLCQ11

Storage Temp:

-20°C

Molecular Weight:

51.8

UNSPSC Code:

12352202