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Human CellExp™ Carbonic Anhydrase IX / CA9, Human Recombinant

Supplier:
Catalogue number:
P1336-10
Size:
10 µg
Product is available in:
  • UK
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  • Europe
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  • Rest of World
£249.00 Estimated delivery Wed 28 Apr
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Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes. CAs form a family of enzymes that catalyse the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. One of the functions of the enzyme in animals is to interconvert carbon dioxide and bicarbonate to maintain acid-base balance in blood and other tissues, and to help transport carbon dioxide out of tissues. The active site of most carbonic anhydrases contains a zinc ion. There are at least five distinct CA families (α, β, γ, δ and ε). Carbonic anhydrase 9 (CA9 / CAIX), also known as Membrane antigen MN (MN), Renal cell carcinoma-associated antigen G250, which belongs to the alpha-carbonic anhydrase family. CA9 / CAIX with an optimal activity at pH 6.49. Reversible hydration of carbon dioxide. CA IX participates in pH regulation. CA9 may be involved in the control of cell proliferation and transformation. CA-IX appears to be a novel specific biomarker for a cervical neoplasia.

Product Type:

Proteins and peptides

Alternative Names:

CAIX, CA9, CA-IX, G250, MN, P54/58N, pMW1

Storage Temp:

-20°C

Molecular Weight:

36

UNSPSC Code:

12352202

P1336-10

P1336-10