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Human CellExp™ Siglec-2 / CD22, Mouse Recombinant

Supplier:
Catalogue number:
P1330-10
Size:
10 µg
Product is available in:
  • UK
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  • Europe
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  • Rest of World
£122.00 Estimated delivery Wed 21 Apr
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B-cell receptor CD22 is also known as Sialic acid-binding Ig-like lectin 2 (Siglec-2), B-lymphocyte cell adhesion molecule (BL-CAM), T-cell surface antigen Leu-14, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD22 mediates B-cell B-cell interactions, and may be involved in the localisation of B-cells in lymphoid tissues. Siglec-2 / CD22 binds sialylated glycoproteins, one of which is CD45. Siglec2 / CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

Product Type:

Proteins and peptides

Alternative Names:

CD22, SIGLEC2, BL-CAM, Leu-14

Storage Temp:

-20°C

Molecular Weight:

78.3

UNSPSC Code:

12352202

P1330-10

P1330-10