Anti-Connexin 32 Antibody (GJB1/1753)
FC, IF, WB, IHC
Mouse
Human, Mouse and Rat
Mouse / IgG
Monoclonal
Recombinant human GJB1 protein
- Data sheet: View or download
This Ab recognizes a protein of 27-32 kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called connexons that facilitate movement of low molecular_weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane -helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20-connexin isoforms produces channels with distinct permeability and electrical and chemical sensitivities; therefore, one connexin usually cannot fully substitute for another.
-20°C