www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

Anti-Clathrin Antibody (CLC/1421)

Supplier:
Catalogue number:
A1577-100
Size:
100 µg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£505.00 Estimated delivery Wed 21 Apr
Shipping is calculated in checkout

This antibody recognises proteins of 31-44 kDa, which are identified as Clathrin Light Chains (both A & B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60% homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.

Product Type:

Antibodies

Species Reactivity:

Human

Storage Temp:

-20°C

Antibody Host:

Mouse

Antibody Isotype:

Mouse / IgG2b, kappa

Formulation:

Supplied in 10 mM PBS with 0.05% BSA & 0.05% azide

Antibody Type:

Monoclonal

Clone Number:

CLC/1421

UNSPSC Code:

12352203

Anti-Clathrin Antibody (CLC/1421)

Anti-Clathrin Antibody (CLC/1421)