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Anti-CELA3B / ELA3B Antibody (CELA3B/1257)

Supplier:
Catalogue number:
A1574-100
Size:
100 µg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£505.00 Estimated delivery Wed 28 Apr
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This mAb recognises a protein of ~30 kDa, identified as CELA3B (Chymotrypsin like elastase family member 3B). Elastases form a subfamily of serine proteases that hydrolyse many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.

Product Type:

Antibodies

Species Reactivity:

Human, Mouse and Rat

Storage Temp:

-20°C

Antibody Host:

Mouse

Antibody Isotype:

Mouse / IgG1

Formulation:

Supplied in 10 mM PBS with 0.05% BSA & 0.05% azide

Antibody Type:

Monoclonal

Clone Number:

CELA3B/1257

UNSPSC Code:

12352203

Anti-CELA3B / ELA3B Antibody (CELA3B/125

Anti-CELA3B / ELA3B Antibody (CELA3B/1257)