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CAS Number:
911222-45-2
Purity:
≥98% by HPLC
Molecular Weight:
436
Alternative Names:
(S)-1-(5-bromo-4-methyl-2-(morpholin-2-ylmethoxy)phenyl)-3-(5-methylpyrazin-2-yl)urea; Rabusertib
- Data sheet: View or download
- MSDS: View or download
Product Description:
LY-2603618 is a potent, selective and ATP-dependent inhibitor of checkpoint kinase 1 (Chk1) (IC₅₀ = 7 nM). It inhibits Chk1 autophosphorylation and increase DNA damage-mediated Chk1 phosphorylation. Displays antitumor activities.
Storage Temperature:
-20°C