N/A
Shipping is calculated in checkout
This product is no longer available to order.
CAS Number:
908112-43-6
Purity:
≥98% by HPLC
Molecular Weight:
464
Alternative Names:
2-[(trans-4-Hydroxycyclohexyl)amino]-4-[4,5,6,7-tetrahydro-6,6-dimethyl-4-oxo-3-(trifluoromethyl)-1H-indazol-1-yl]benzamide; PF-04928473
- Data sheet: View or download
- MSDS: View or download
Product Description:
SNX-2112 is a potent heat-shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. SNX-2112 selectively accumulates in tumors compared to normal tissues and binds to the N-terminal adenosine triphosphate binding site of Hsp90, inhibiting its activity. This results in the proteasomal degradation of oncogenic client proteins, which prevents signaling through these client proteins, induces apoptosis and inhibits tumor cell proliferation.
Storage Temperature:
-20°C