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SNX-2112

Catalogue number:
Supplier:
BioVision
Size:
25 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
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CAS Number:

908112-43-6

Purity:

≥98% by HPLC

Molecular Weight:

464

Alternative Names:

2-[(trans-4-Hydroxycyclohexyl)amino]-4-[4,5,6,7-tetrahydro-6,6-dimethyl-4-oxo-3-(trifluoromethyl)-1H-indazol-1-yl]benzamide; PF-04928473

Product Description:

SNX-2112 is a potent heat-shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. SNX-2112 selectively accumulates in tumors compared to normal tissues and binds to the N-terminal adenosine triphosphate binding site of Hsp90, inhibiting its activity. This results in the proteasomal degradation of oncogenic client proteins, which prevents signaling through these client proteins, induces apoptosis and inhibits tumor cell proliferation.

Storage Temperature:

-20°C

SNX-2112
SNX-2112