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AN-2728

Supplier:
Catalogue number:
B2220-5
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£96.00 Estimated delivery Wed 28 Apr
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AN-2728 is a boron-based, topical anti-inflammatory agent that acts as a phosphodiesterase 4 (PDE4) inhibitor (IC₅₀ = 0.11 µM). It is less potent against PDE1A, PDE3A, and PDE7A (IC₅₀s = 6.12, 6.41, and 0.73 µM, respectively). AN-2728 suppresses the release of the proinflammatory cytokines TNF-α, IL-2, INF-γ, IL-5, and IL-10 with IC₅₀ values of 0.50, 0.59, 0.72, 2.25, and 2.58 µM, respectively.

Product Type:

Biochemicals

CAS Number:

906673-24-3

Storage Temp:

-20°C

Compound Purity:

≥98% by HPLC

Molecular Weight:

251.04

UNSPSC Code:

12352200

AN-2728

AN-2728