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AT7867

Supplier:
Catalogue number:
B2178-1
Size:
1 mg
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
£96.00 Estimated delivery Wed 28 Apr
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AT7867 is a potent inhibitor of Akt isoforms Akt1, 2, and 3 (IC₅₀s = 32, 17, and 47 nM, respectively). It also inhibits p70S6 kinase and PKA (IC₅₀s = 85 and 20 nM, respectively), but is without effect against a panel of other kinases. AT7867 inhibits growth and induces apoptosis in a variety of cancer cell lines in vitro and suppresses tumor growth of PTEN-deficient xenografts in mice.

Product Type:

Biochemicals

CAS Number:

857531-00-1

Storage Temp:

-20°C

Compound Purity:

≥97% by HPLC

Molecular Weight:

337.9

UNSPSC Code:

12352200

AT7867

AT7867