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CAS Number:
857531-00-1
Purity:
≥97% by HPLC
Molecular Weight:
337
Alternative Names:
4-(4-Chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]piperidine
- Data sheet: View or download
- MSDS: View or download
Product Description:
AT7867 is a potent inhibitor of Akt isoforms Akt1, 2, and 3 (IC₅₀s = 32, 17, and 47 nM, respectively). It also inhibits p70S6 kinase and PKA (IC₅₀s = 85 and 20 nM, respectively), but is without effect against a panel of other kinases. AT7867 inhibits growth and induces apoptosis in a variety of cancer cell lines in vitro and suppresses tumor growth of PTEN-deficient xenografts in mice.
Storage Temperature:
-20°C
