www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

Abexinostat

Supplier:
Catalogue number:
B2202-5
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£147.00 Estimated delivery Wed 21 Apr
Shipping is calculated in checkout

Abexinostat is a broad-spectrum phenyl hydroxamic acid inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity. It inhibits several isoforms of HDAC, resulting in an accumulation of highly acetylated histones, followed by the induction of chromatin remodeling. Abexinostat has been shown to inhibit homologous recombination (HR) activity by inhibiting the expression of RAD51. RAD51, a homologue of bacterial RecA, assists in the repair of DNA double-strand breaks (DSBs).

Product Type:

Biochemicals

CAS Number:

783355-60-2

Storage Temp:

-20°C

Compound Purity:

≥96% by HPLC

Molecular Weight:

397.42

UNSPSC Code:

12352200

Abexinostat

Abexinostat