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C K-666

Catalogue number:
Supplier:
BioVision
Size:
5 mg _$$_
Product is available in:
  • UK
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CAS Number:

442633-00-3

Purity:

≥98% by TLC

Molecular Weight:

296

Alternative Names:

2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide

Product Description:

CK-666 is a potent, selective and reversible inhibitor of ARP2/3 complex (actin related proteins 2 and 3) with an IC₅₀ = 4 µM for human ARP2/3. Blocks actin nucleation and radically alters lamellipodial actin architecture, suspended cell shape and the cell spreading process. CK-666 attenuates BBB dysfunction induced by methamphetamine. A key new tool for studying actin assembly and the diverse range of actin-related processes in normal and pathophysiology.

Storage Temperature:

-20°C

C K-666
C K-666