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C K-666

Supplier:
Catalogue number:
B2147-5
Size:
5 mg
Product is available in:
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£96.00 Estimated delivery Wed 28 Apr
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CK-666 is a potent, selective and reversible inhibitor of ARP2/3 complex (actin related proteins 2 and 3) with an IC₅₀ = 4 µM for human ARP2/3. Blocks actin nucleation and radically alters lamellipodial actin architecture, suspended cell shape and the cell spreading process. CK-666 attenuates BBB dysfunction induced by methamphetamine. A key new tool for studying actin assembly and the diverse range of actin-related processes in normal and pathophysiology.

Product Type:

Biochemicals

CAS Number:

442633-00-3

Storage Temp:

-20°C

Compound Purity:

≥98% by TLC

Molecular Weight:

296.3

UNSPSC Code:

12352200

C K-666

C K-666