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BPTES is an allosteric glutaminase (GLS1) inhibitor (IC₅₀ = 3.3 µM). Displays selectivity for GLS1 over GLS2 and γ-glutamyl transpeptidase. Induces cell death of P493 human lymphoma B cells in vitro and reduces tumor volume of P493 cell xenografts in mice.
Product Type:
Biochemicals
CAS Number:
314045-39-1
Storage Temp:
-20°C
Compound Purity:
≥98% by HPLC
Molecular Weight:
524.68
UNSPSC Code:
12352200
