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LOXO-195

Supplier:
Catalogue number:
B2226-1
Size:
1 mg
Product is available in:
  • UK
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  • Rest of World
£186.00 Estimated delivery Wed 28 Apr
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LOXO-195 is a potent and selective TRK (tropomyosin-related-kinase) inhibitor, with potential anticancer activity. LOXO-195 specifically targets and binds to TRK, including the fusion proteins containing sequences from neurotrophic tyrosine receptor kinase (NTRK) types 1 (NTRK1), 2 (NTRK2), and 3 (NTRK3). This prevents neurotrophin-TRK interaction and TRK activation, which results in both the induction of cellular apoptosis and the inhibition of cell growth in tumors that overexpress TRK and/or express NTRK fusion proteins.

Product Type:

Biochemicals

CAS Number:

2097002-61-2

Storage Temp:

-20°C

Compound Purity:

≥98% by HPLC

Molecular Weight:

380.43

UNSPSC Code:

12352200

LOXO-195

LOXO-195