www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

PF-06840003

Supplier:
Catalogue number:
B2218-5
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£428.00 Estimated delivery Wed 28 Apr
Shipping is calculated in checkout

PF-06840003 is a highly selective orally bioavailable indoleamine 2,3-dioxygenase -1 (IDO-1) inhibitor (IC₅₀ = 0.15 µM for human enzyme). It inhibits IDO-1-mediated production of kynurenine induced by IFN-γ in HeLa cells (IC₅₀ = 1.8 µM) and by LPS and IFN-γ in THP-1 cells and human-derived whole blood ex vivo (IC₅₀s = 1.7 and 4.7 µM, respectively).

Product Type:

Biochemicals

CAS Number:

198474-05-4

Storage Temp:

-20°C

Compound Purity:

≥98% by HPLC

Molecular Weight:

232.21

UNSPSC Code:

12352200

PF-06840003

PF-06840003