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YU238259 is a potent inhibitor of Homology-Dependent DNA Repair (HDR). YU238259 displays potent synthetic lethality in the setting of DNA damage response and DNA repair defects. YU238259 specifically inhibits homology-dependent DNA repair, but not non-homologous end-joining, in cell-based GFP reporter assays.
Product Type:
Biochemicals
CAS Number:
1943733-16-1
Storage Temp:
-20°C
Compound Purity:
≥98% by HPLC
Molecular Weight:
459.94
UNSPSC Code:
12352200