www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

IACS-010759

Catalogue number:
Supplier:
BioVision
Size:
1 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
N/A
Shipping is calculated in checkout
This product is no longer available to order.
CAS Number:

1570496-34-2

Purity:

≥98% by HPLC

Molecular Weight:

562

Alternative Names:

5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole

Product Description:

IACS-010759 is a potent and selective Oxidative Phosphorylation Inhibitor (IC₅₀ < 10 nM) with potential antineoplastic activity. IACS-010759 robustly inhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS, likely owing to a combination of energy depletion and reduced aspartate production that leads to impaired nucleotide biosynthesis.

Storage Temperature:

-20°C

IACS-010759
IACS-010759