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G-749 is a potent FLT3 kinase inhibitor that displays potent and sustained inhibition of the FLT3 wild type and mutants including FLT3-ITD, FLT3-D835Y, FLT3-ITD/N676D, and FLT3-ITD/F691L in cellular assays. G-749 retains its inhibitory potency in various drug-resistance milieus such as patient plasma, FLT3 ligand surge, and stromal protection.
Product Type:
Biochemicals
CAS Number:
1457983-28-6
Storage Temp:
-20°C
Compound Purity:
≥98% by HPLC
Molecular Weight:
521.41
UNSPSC Code:
12352200
