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AZD-3965

Catalogue number:
Supplier:
BioVision
Size:
1 mg _$$_
Product is available in:
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CAS Number:

1448671-31-5

Purity:

≥98% by HPLC

Molecular Weight:

515

Alternative Names:

(S)-5-(4-hydroxy-4-methylisoxazolidine-2-carbonyl)-1-isopropyl-3-methyl-6-((3-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione

Product Description:

AZD-3965 is a potent and selective monocarboxylate transporter 1 (MCT1) inhibitor with a binding affinity of 1.6 nM; it is 6-fold selective over MCT2 and does not inhibit MCT4 even at 10 µM. AZD 3965 increases intratumor lactate levels and decreases tumor growth in mice bearing COR-L103 small cell lung cancer (SCLC) xenografts.

Storage Temperature:

-20°C

AZD-3965
AZD-3965