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CAS Number:
1203494-49-8
Purity:
≥98% by HPLC
Molecular Weight:
453
Alternative Names:
3-((4-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)sulfonyl)-1,4-diazepan-1-yl)sulfonyl)aniline; ML-203
- Data sheet: View or download
- MSDS: View or download
Product Description:
DASA-58 is a selective activator of pyruvate kinase M2 (PKM2) (AC₅₀ = 38 nM). DASA-58 converts PKM2 to a constitutively active enzyme state that is resistant to inhibition by tyrosine-phosphorylated protein. In cancer, the altered glucose metabolism can be influenced by the regulatory properties of PKM2.
Storage Temperature:
-20°C
