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BS-181 dihydrochloride

Catalogue number:
Supplier:
BioVision
Size:
5 mg _$$_
Product is available in:
  • UK
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CAS Number:

1092443-52-1

Purity:

≥97% by HPLC

Molecular Weight:

453

Alternative Names:

N5-(6-Aminohexyl)-3-(1-methylethyl)-N7-(phenylmethyl)pyrazolo[1,5-a]pyrimidine-5,7-diamine dihydrochloride

Product Description:

BS-181 dihydrochloride is a potent and selective CDK7 inhibitor (IC₅₀ = 21 nM). It displays >40-fold selectivity for CDK7 over others CDKs. Promotes cell cycle arrest and apoptosis in a range of cancer cells in vitro and inhibits MCF-7 tumor xenograft growth in mice.

Storage Temperature:

-20°C

BS-181 dihydrochloride
BS-181 dihydrochloride