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PicoProbeTM Methylglyoxal Assay Kit (Fluorometric)

Supplier:
Catalogue number:
K461-100
Size:
100 assays
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£594.00 Estimated delivery Wed 28 Apr
Shipping is calculated in checkout

Methylglyoxal ( mg, 2-oxopropanal, pyruvic aldehyde), a by-product of glycolysis, is a highly toxic, reactive dicarbonyl compound. It causes non-enzymatic glycation of proteins which yields irreversible advanced glycation end products (AGEs), leading to cross-linking or degradation of proteins. mg is associated with several pathologies including diabetes, aging and neurodegenerative diseases. Furthermore, recent studies have suggested that mg may induce carbonyl stress-type schizophrenia. BioVision’s PicoProbeTM Methylglyoxal Assay Kit (Fluorometric) can detect mg using an enzyme-coupled reaction which reduces the fluorogenic probe. The reduced fluorophore produces a stable signal (Ex/Em= 535/587nm), which is directly proportional to the amount of mg in samples. The assay is simple, reproducible and can specifically detect as low as 6 pmol of mg in a 100 µl reaction.

  • Data sheet/protocol: View or download
  • MSDS: View or download
  • Applications: This Kit provides a simple, highly sensitive in vitro assay for detecting Methylglyoxal levels in biological samples.
Product Type:

Biochemical and cellular assays

Storage Temp:

-20°C

UNSPSC Code:

41116133

PicoProbeTM Methylglyoxal Assay Kit (Flu

PicoProbeTM Methylglyoxal Assay Kit (Fluorometric)