XMD17-109
Supplier:
Catalogue number:
CAY25448-1 mg
Size:
1 mg
Product is available in:
£33.00
Estimated delivery Tue 4 May
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A selective ERK5 inhibitor (IC50 = 0.162 µM in an enzyme assay); selective for ERK5 over a panel of more than 200 kinases at 10 µM; inhibits ERK5 phosphorylation (IC50 = 0.09 µM in HeLa cells); decreases AP-1 transcriptional activity (EC50 = 4.2 µM); inhibits human recombinant LRRK2[G2019S] (IC50 = 0.339 µM in an enzyme assay)
Product Type:
Biochemicals
CAS Number:
1435488-37-1
Alternative Names:
11-cyclopentyl-2-[[2-ethoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5,11-dihydro-5-methyl-6h-pyrimido[4,5-b][1,4]benzodiazepin-6-one, erk5-in-1
Storage Temp:
-20°C
Formulation:
A crystalline solid
Compound Purity:
≥98%
UNSPSC Code:
12352200
