Concanamycin A
Catalogue number:
B2091-25
Supplier:
BioVision
Size:
25 µg _$$_
Product is available in:
N/A
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CAS Number:
80890-47-7
Purity:
≥95%
Molecular Weight:
866
Alternative Names:
[(2R,3S,4R,6R)-6-[(2S,4R,5S)-2-[4-[(4E,6E,14E,16Z)-11-ethyl-10,12-dihydroxy-3,17-dimethoxy-7,9,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6,14,16-tetraen-2-yl]-3-hydroxypentan-2-yl]-2-hydroxy-5-methyl-6-[(E)-prop-1-enyl]oxan-4-yl]oxy-4-hydroxy-2-methyl
- Data sheet: View or download
- MSDS: View or download
Product Description:
Concanamycin A is a specific inhibitor of V-type (vacuolar) H+-ATPase. It displays > 2000-fold selectivity over other H+-ATPases (IC₅₀ values are 9.2, > 20000, > 20000 and > 20000 nM for yeast V-type, F-type, P-type H⁺-ATPases and porcine P-type Na⁺,K⁺-ATPase respectively). Concanamycin A blocks cell surface expression of viral glycoproteins without affecting their synthesis and, at 0.8 µM, prevents entry of influenza virus into cells.
Storage Temperature:
-20°C
