HDAC6 Antibody
Catalogue number:
3606-30T
Supplier:
BioVision
Size:
30 µg _$$_
Product is available in:
N/A
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Applications:
Western blot, Immunohistochemistry
Antibody Host:
Rabbit
Species Reactivity:
Human, mouse, rat
Antibody Isotype:
Rabbit IgG
Antibody Type:
Polyclonal
Immunogen:
Synthetic peptide mapping to the N-terminus of mouse HDAC-6
- Data sheet: View or download
Product Description:
Human HDAC6 (1215 a.a. residues) possesses two separate putative catalytic domains, both of which are fully functional and contribute independently to the overall activity of HDAC6. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. HDAC6 may participate in coordinating expression of a group of genes involved in the remoldeling of chromatin during cell differentiation.
Storage Temperature:
-20°C