ExoFLARE CD81 Kit: expression construct and impermeable dye

ExoFLARE™ exosome tracking system. ExoFLARES™ utilize a combination of a FLARE (FLuorescence Activating Response Element) protein tag together with a pro-fluorophore dye. Neither the protein or dye fluoresce in isolation. When the protein binds to the dye, it causes a change in structure which results in fluorescence. The dye and protein form an unstable bond with continuous turnover of the dye. This results in sustained fluorescence without the levels of photo-bleaching associated with fluorescent proteins. This allows ExoFLARES™ to be monitored for extensive periods to allow tracking of movement of dyes.