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sCD59, Human, ELISA kit

Supplier:
Catalogue number:
HK374-02
Size:
2 x 96 detections
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£1165.00 Estimated delivery Thu 14 Jul
Shipping is calculated in checkout

CD59 is a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. Complement activation ultimately leads to formation of the cytotoxic, poreforming membrane attack complex (MAC), the main effector of complement-mediated tissue damage. Insertion of the MAC into cell membranes induces the release of cytokines and growth factors that promote inflammation, thrombosis, and cell proliferation. CD59 is a complement regulatory protein ubiquitously expressed on mammalian cell surfaces and it specifically inhibits MAC formation and thereby protects €œself€ cells from complement-mediated damage. The protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in the CD59 gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. CD59 was demonstrated to be present in plasma/serum of healthy individuals in levels ranging from 22 to 119 ng/ml.

Product Type:

ELISAs

Storage Temp:

Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at lea

UNSPSC Code:

41116126

HK374-02 sCD59, Human, ELISA kit

HK374-02 sCD59, Human, ELISA kit

HK374-02 sCD59, Human, ELISA kit

HK374-02 sCD59, Human, ELISA kit

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