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Mouse Anti-Chicken CD8α-APC

Supplier:
Catalogue number:
8220-11
Size:
0.1 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£358.00 Estimated delivery Fri 15 Jul
Shipping is calculated in checkout

In the chicken, the CD8 molecule is present in two forms - (i) a homodimer of two α chains and (ii) a heterodimer of an α chain and a β chain. While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8α- and CD8β-chains, a relatively large proportion of the CD8+ TCRγδ cells in the spleens of embryos and young chicks express only the α-chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved but there is a population of TCRγδ CD8αβ cells in the chicken that is not found in rodents. Chicken CD8 is expressed on approximately 80% of thymocytes, 15% of blood mononuclear cells, and 50% of spleen cells but less than 1% of cells in the bursa and bone marrow. The monoclonal antibody CT-8 recognises the CD8α chain and has been shown to react to a polymorphic determinant in turkey.

Chicken peripheral blood lymphocytes wer
Product Type:

Antibodies

Species Reactivity:

Chicken, Turkey, Guinea Fowl, Pigeon

Immunogen:

Chicken thymocytes and Ig-negative blood leukocytes

Storage Temp:

2 - 8°C

Antibody Host:

Mouse

Antibody Isotype:

IgG1

Antibody Type:

Monoclonal

Clone Number:

CT-8

UNSPSC Code:

12352203

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