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Rat Anti-Mouse CD4-PACBLU

Supplier:
Catalogue number:
1540-26
Size:
0.1 mg
Product is available in:
  • UK
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£219.00 Estimated delivery Fri 15 Jul
Shipping is calculated in checkout

CD4 is a type I transmembrane glycoprotein expressed on most thymocytes and the helper/inducer subpopulation of mature T lymphocytes of all mouse strains tested. CD4 has also been detected at low density on pluripotent hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic lymphoid precursors. The CD4 antigen functions as a co-receptor, interacting with class II major histocompatability complex (MHC) molecules in the recognition of foreign antigens by T cells. In vivo and in vitro treatment with the GK1.5 monoclonal antibody effectively depletes CD4+ cells. GK1.5 also blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.

BALB/c mouse splenocytes were stained wi
Product Type:

Antibodies

Alternative Names:

L3T4, Ly-4

Species Reactivity:

Mouse

Immunogen:

Mouse CTL clone V4

Storage Temp:

2 - 8°C

Antibody Host:

Rat

Antibody Isotype:

IgG2b

Antibody Type:

Monoclonal

Clone Number:

GK1.5

UNSPSC Code:

12352203

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