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79356-08-4
≥85%
A solid
917.1
(2r,3s,4s,5r,6s)-6-[(1r)-1-[(2s,5r,7s,8r,9s)-2-[(2s,2'r,3's,5r,5'r)-3'-[(2,6-dideoxy-3,4-di-o-methyl-β-l-arabino-hexopyranosyl)oxy]octahydro-2-methyl-5'-[(2s,3s,5r,6s)-tetrahydro-6-hydroxy-3,5,6-trimethyl-2h-pyran-2-yl][2,2'-bifuran]-5-yl]-9-hydroxy-2,8-d
- Data sheet: View or download
- MSDS: View or download
A polyether ionophore antibiotic; selectively binds to monovalent cations over divalent cations; active against Gram-positive bacteria (MICs = 0.9-125 µg/ml); It reduces the viability of asexual and gametocyte P. falciparum parasites (EC50s = 1.3 and 14.8 nM, respectively); reduces P. berghei transmission in a mouse model of malaria at 4 and 8 mg/kg; reduces the severity of lesions and completely protects chicks against mortality in a model of E. tenella-induced coccidiosis at 5-10 ppm in the diet
-20°C
