AN3365 (hydrochloride)
Catalogue number:
CAY20572-10 mg
Supplier:
Size:
10 mg _$$_
Product is available in:
£345.00
Estimated delivery Tue 30 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1234563-16-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
273.5
Alternative Names:
3-[[(3s)-3-(aminomethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaborol-7-yl]oxy]-1-propanol, monohydrochloride, epetraborole, gsk2251052
- Data sheet: View or download
- MSDS: View or download
Product Description:
A LeuRS inhibitor (IC50 = 0.31 µM for the E. coli enzyme); active against a variety of bacteria, including MDR clinical isolates (MICs = 2-8 µg/ml); inhibits protein, RNA, DNA, and fatty acid synthesis in E. coli (IC50s = 8.3, 105, 366, and 396 µg/ml, respectively); reduces the number of CFUs in neutropenic mouse thigh models of E. coli or P. aeruginosa infection at 30 mg/kg
Storage Temperature:
-20°C
