£432.00
Estimated delivery Wed 1 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
401907-26-4
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
423.6
Alternative Names:
n-[4-[[[[[[4-(1,1-dimethylethyl)phenyl]methyl]amino]thioxomethyl]amino]methyl]-2-fluorophenyl]-methanesulfonamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
A TRPV1 antagonist; inhibits capsaicin-induced calcium uptake in CHO cells expressing rat TRPV1 (EC50 = 9.2 nM); inhibits capsaicin-induced release of somatostatin, substance P, and CGRP from isolated rat trachea (IC50s = 227-491 nM); inhibits capsaicin-induced hypothermia and hypotension in rats at 2 and 0.4 mg/kg, respectively; reduces the number of wiping movements induced by ocular administration of capsaicin in rats at 2 mg/kg
Storage Temperature:
-20°C
