Dimethylamino Parthenolide
Catalogue number:
CAY20436-25 mg
Supplier:
Size:
25 mg _$$_
Product is available in:
£354.00
Estimated delivery Fri 3 May
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
791595-09-0
Purity:
≥99%
Formulation:
A crystalline solid
Molecular Weight:
293.4
Alternative Names:
(1ar,4e,7as,8r,10as,10br)-8-[(dimethylamino)methyl]-2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-oxireno[9,10]cyclodeca[1,2-b]furan-9(1ah)-one, dmapt, lc-1
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of NF-κB; inhibits the binding of the p65 subunit of NF-κB to DNA by 75% at 50 µM; decreases intracellular GSH levels in, and inhibits the migration of, MDA-MB-231 cells at 25 µM; induces necrosis in MDA-MB-231 cells, an effect that can be reversed by N-acetyl cysteine, apocynin, or necrostatin-1; decreases tumor volume in an MDA-MB-231 mouse xenograft model at 50 mg/kg
Storage Temperature:
-20°C