Tel: +44 (0)1223 316 855
life science research products, biological research products, biotechnology
close ...


Supplier:
Product types:
Fast & Convenience HDAC Activity Assays Kits
Rapid Endotoxin Removal Kit - ToxOut™
High Quality Affordable Small Molecule Compounds

Receive High Quality Leukaemia & Lymphoma Biospeciemens Within 24 Hours

 

SIRT6 Antibody - 6692-100 - 100 µg - BioVision - antibodies

SIRT6 Antibody
print page
Size: 100 µg
£339.00
GBP | Euro | USD
Add to basket
Catalogue number:
6692-100
Name:
SIRT6 Antibody
Supplier:
Availability:

Human Sirtuins function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. Sirtuin 6 (SIRT6) is a NAD-dependent protein deacetylase with activity towards Lys-9 and Lys-56 of histone H3. It modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. It is required for genomic stability and for normal IGF1 serum levels and normal glucose homeostasis. It also regulates cellular senescence and apoptosis. Unlike most sirtuins, SIRT6 preferentially removes long-chain fatty-acyl, rather than acetyl, protein modifications. This activity regulates secretion of the inflammation-associated protein TNF-α.

Data sheet:

Click to view / download

Applications:

Western blot

Product Type:
Antibodies
Alternative Names:
SIRT6, NAD-dependent Deacetylase Sirtuin-6; Mono-ADP-ribosyltransferase Sirtuin 6; SIR2-like Protein 6; SIR2L6
Species Reactivity:
Human, Mouse
Immunogen:
Recombinant Human Sirtuin 6 (Cat # 7699)
Storage Temp:
-20°C
Antibody Host:
Rabbit
Antibody Isotype:
Rabbit IgG
Antibody Type:
Polyclonal
UNSPSC Code:
12352203
Contact Our Customer Service Team